The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

Mar. 16, 2012
Applicants:

Benzhong Tang, Hong Kong, CN;

Yang Liu, Hong Kong, CN;

Wing Yip Lam, Hong Kong, CN;

Yong Yu, Hong Kong, CN;

Inventors:

Benzhong Tang, Hong Kong, CN;

Yang Liu, Hong Kong, CN;

Wing Yip Lam, Hong Kong, CN;

Yong Yu, Hong Kong, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/448 (2006.01); C09B 57/00 (2006.01); C07D 207/444 (2006.01); C09B 69/00 (2006.01);
U.S. Cl.
CPC ...
C07D 207/444 (2013.01); C07D 207/448 (2013.01); C09B 57/00 (2013.01); C09B 69/008 (2013.01); Y10T 436/182 (2015.01);
Abstract

Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for detecting thiol groups in biomolecules. Also provided is a dye molecule, a biosensor or a bioprobe comprising the luminogen compound of formula (I) in use for detecting thiol groups in biomolecules. The detection method of the present subject matter not only has high thio-selectivity and sensitivity, but also is rapid, convenient and handy.


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