The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

Oct. 26, 2011
Applicants:

Boulos Zacharie, Laval, CA;

Christopher Penney, Pierrefonds, CA;

Shaun Abbott, Pointe-Claire, CA;

Lyne Gagnon, Laval, CA;

Brigitte Grouix, Montreal, CA;

Pierre Laurin, Ville Mont-Royal, CA;

Jean-françois Bienvenu, Quebec, CA;

Inventors:

Boulos Zacharie, Laval, CA;

Christopher Penney, Pierrefonds, CA;

Shaun Abbott, Pointe-Claire, CA;

Lyne Gagnon, Laval, CA;

Brigitte Grouix, Montreal, CA;

Pierre Laurin, Ville Mont-Royal, CA;

Jean-François Bienvenu, Quebec, CA;

Assignee:

PROMETIC BIOSCIENCES INC., Laval, Quebec, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 59/90 (2006.01); C07C 62/38 (2006.01); C07C 65/32 (2006.01); C07C 69/92 (2006.01); C07C 217/84 (2006.01); C07C 225/22 (2006.01); C07C 229/18 (2006.01); C07C 323/20 (2006.01); C07C 323/52 (2006.01); C07C 323/62 (2006.01); A61K 31/192 (2006.01); A61K 31/196 (2006.01); A61K 31/222 (2006.01); A61K 31/235 (2006.01); C07C 59/68 (2006.01); C07C 59/84 (2006.01);
U.S. Cl.
CPC ...
C07C 59/90 (2013.01); A61K 31/192 (2013.01); A61K 31/196 (2013.01); A61K 31/222 (2013.01); A61K 31/235 (2013.01); C07C 59/68 (2013.01); C07C 59/84 (2013.01); C07C 62/38 (2013.01); C07C 65/32 (2013.01); C07C 69/92 (2013.01); C07C 217/84 (2013.01); C07C 225/22 (2013.01); C07C 229/18 (2013.01); C07C 323/20 (2013.01); C07C 323/52 (2013.01); C07C 323/62 (2013.01); C07C 2102/08 (2013.01);
Abstract

Phenylketone carboxylate compounds of Formula I, wherein n=2-6; R═C(0); —OC(O)— or —CH(OH)—; A is (CH2)mCOOH, W(CH2)mCOOH or YCH(COOH)((CH2)pCH3) when B is Ft B is (CH2)mCOOH, W(CH2)mCOOH or YCH(COOH)((CH2)pCH3) when A is Ft or A and B form a 5-7 membered cycloalkyl substituted with COOFt W=0, S or NFt Y=0,S,NH or CH2; m=0-2; p=1-7; have been prepared. These compounds and their pharmaceutically acceptable salts have beneficial therapeutic effects to prevent or treat a condition related to (l) blood disorders, (ii) inflammation related diseases, (iii) renal disorders and/or renal disorders complications, or (iv) fibrosis-related organ dysfunction.


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