The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

Oct. 23, 2013
Applicant:

Alteogen Inc., Daejeon, KR;

Inventors:

Soon Jae Park, Daejoen, KR;

Seong-Kyu Kim, Daejeon, KR;

Assignee:

ALTEOGEN INC., Daejeon, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 47/02 (2006.01); C07K 14/705 (2006.01); C01C 1/16 (2006.01); C09K 15/20 (2006.01); A61K 38/17 (2006.01); A61K 47/26 (2006.01); A61K 9/08 (2006.01);
U.S. Cl.
CPC ...
A61K 47/02 (2013.01); A61K 9/08 (2013.01); A61K 38/1793 (2013.01); A61K 47/26 (2013.01); C01C 1/164 (2013.01); C07K 14/70578 (2013.01); C09K 15/20 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to a composition for stabilizing a fusion protein of a physiologically active protein and an Fc domain, and more particularly to a method of stabilizing a fusion protein of a protein and an Fc domain using a composition containing an ammonium salt or a combination of an ammonium salt and succinate. The composition containing an ammonium salt or a combination of an ammonium salt and succinate according to the present invention can effectively inhibit the aggregation of the protein-Fc domain fusion protein, and thus enables the fusion protein to be stored for a long period of time. Accordingly, the composition can be widely used in the medical field that uses the protein-Fc domain fusion protein.


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