The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2016
Filed:
Mar. 13, 2014
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Daniel C. H. Lin, Redwood City, CA (US);
Jinghong Wang, Palo Alto, CA (US);
Yang Li, Mountain View, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); A61B 5/145 (2006.01); C12N 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61B 5/14532 (2013.01); C12N 9/20 (2013.01); C12Y 301/01004 (2013.01);
Abstract
Methods of treating or ameliorating metabolic diseases using a PLA2G12A polypeptide or PLA2G12A mutant polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes mellitus, obesity, dyslipidemia elevated glucose levels, elevated insulin levels and diabetic nephropathy.