The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9474770 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 25, 2016

Filed:

Aug. 10, 2012
Applicants:

Kosaku Kinoshita, Tokyo, JP;

Katsuhisa Tanjoh, Tokyo, JP;

Akihiro Noda, Tokyo, JP;

Atsushi Sakurai, Tokyo, JP;

Tohru Tanaka, Tokyo, JP;

Kiwamu Takahashi, Tokyo, JP;

Motowo Nakajima, Tokyo, JP;

Fuminori Abe, Tokyo, JP;

Inventors:

Kosaku Kinoshita, Tokyo, JP;

Katsuhisa Tanjoh, Tokyo, JP;

Akihiro Noda, Tokyo, JP;

Atsushi Sakurai, Tokyo, JP;

Tohru Tanaka, Tokyo, JP;

Kiwamu Takahashi, Tokyo, JP;

Motowo Nakajima, Tokyo, JP;

Fuminori Abe, Tokyo, JP;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 33/26 (2006.01); A61K 31/197 (2006.01); A61K 31/28 (2006.01); A61K 31/295 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 33/26 (2013.01); A61K 31/197 (2013.01); A61K 31/28 (2013.01); A61K 31/295 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention provides a sepsis therapeutic drug useful for prophylaxis and treatment of sepsis. A prophylactic agent and/or a therapeutic agent for sepsis containing 5-aminolevulinic acid (5-ALA) or a derivative thereof or a pharmacologically acceptable salt of 5-ALA or the derivative as an active ingredient is prepared. The prophylactic agent and/or the therapeutic agent preferably contains a metal-containing compound such as ferrous sodium citrate in addition to the ALAs. Preferred examples of the ALAs include ALA; various esters of ALA such as methyl, ethyl, propyl, butyl, and pentyl esters; and hydrochlorides, phosphates, sulfates of ALA and the esters.


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