The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2016
Filed:
Sep. 27, 2012
Kansas State University Research Foundation, Manhattan, KS (US);
The Ohio State University, Columbus, OH (US);
Wichita State University, Wichita, KS (US);
Kyeong-Ok Chang, Manhattan, KS (US);
Yunjeong Kim, Manhattan, KS (US);
William C. Groutas, Wichita, KS (US);
Duy Hua, Manhattan, KS (US);
Linda J. Saif, Wooster, OH (US);
Kansas State University Research Foundation, Manhattan, KS (US);
The Ohio State University, Columbus, OH (US);
Wichita State University, Wichita, KS (US);
Abstract
Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl α-ketoamides, peptidyl bisulfate salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis A virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus.