The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

Apr. 30, 2012
Applicants:

Edda Spiekerkoetter, Stanford, CA (US);

Marlene Rabinovitch, Stanford, CA (US);

Philip A. Beachy, Stanford, CA (US);

David Solow-cordero, Stanford, CA (US);

Inventors:

Edda Spiekerkoetter, Stanford, CA (US);

Marlene Rabinovitch, Stanford, CA (US);

Philip A. Beachy, Stanford, CA (US);

David Solow-Cordero, Stanford, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/436 (2006.01);
U.S. Cl.
CPC ...
A61K 31/436 (2013.01);
Abstract

A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.


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