The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2016

Filed:

Mar. 12, 2013
Applicant:

Regents of the University of Minnesota, Minneapolis, MN (US);

Inventors:

Jaime Freddy Modiano, Roseville, MN (US);

Aric Mathew Frantz, Hampton, MN (US);

Timothy David O'Brien, Cokato, MN (US);

Aaron Lyman Sarver, St. Paul, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); A61K 31/196 (2006.01); A61K 31/475 (2006.01); A61K 31/573 (2006.01); A61K 31/655 (2006.01); A61K 31/664 (2006.01); A61K 31/704 (2006.01); A61K 38/50 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/196 (2013.01); A61K 31/475 (2013.01); A61K 31/573 (2013.01); A61K 31/655 (2013.01); A61K 31/664 (2013.01); A61K 31/704 (2013.01); A61K 38/50 (2013.01); G01N 33/57407 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01);
Abstract

A method for differentiating forms of lymphoma involves analyzing a tumor tissue sample from a subject for expression of CD28, ABCA5, CCDC3, and SMOC2. The CD28:ABCA5 expression ratio differentiates T-cell tumors from B-cell tumors. The CCDC3:SMOC2 expression ratio differentiates different T-cell tumors. The method can further include administering to the subject from whom the sample was obtained an appropriate treatment for the form lymphoma identified by performing the method.


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