The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2016
Filed:
Sep. 07, 2012
Applicants:
William Jeremy Blake, Jamaica Plain, MA (US);
Daniel Klein-marcuschamer, San Francisco, CA (US);
Inventors:
William Jeremy Blake, Jamaica Plain, MA (US);
Daniel Klein-Marcuschamer, San Francisco, CA (US);
Assignee:
GreenLight Biosciences, Inc., Medford, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/18 (2006.01); C12N 15/52 (2006.01); C12N 9/12 (2006.01); C12N 9/00 (2006.01); C12N 9/02 (2006.01); C12N 9/06 (2006.01);
U.S. Cl.
CPC ...
C12P 17/184 (2013.01); C12N 9/0008 (2013.01); C12N 9/0026 (2013.01); C12N 9/1217 (2013.01); C12N 9/93 (2013.01); C12N 15/52 (2013.01); C12Y 102/01041 (2013.01); C12Y 105/99008 (2013.01); C12Y 207/02011 (2013.01); C12Y 603/04016 (2013.01); C12Y 603/05005 (2013.01); Y02P 20/52 (2015.11);
Abstract
Provided herein are cell-free systems for generating carbapenems, e.g., a compound of the Formula (I): or salts thereof; wherein, R, R, R, R, R, and Rare defined herein. Also provided are pharmaceutical compositions comprising a compound generated by the inventive cell-free system, and use of these compounds and compositions for the treatment of bacterial infections.