The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2016
Filed:
Apr. 09, 2014
Applicants:
Liliane Goetsch, Ayze, FR;
Thierry Wurch, Machilly, FR;
Cédric Bes, Nantes, FR;
Inventors:
Assignee:
PIERRE FABRE MEDICAMENT, Boulogne-Billancourt, FR;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01); A61K 31/337 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); A61K 31/555 (2006.01); A61K 31/7068 (2006.01); A61K 33/24 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 31/337 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); A61K 31/555 (2013.01); A61K 31/7068 (2013.01); A61K 33/24 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/53 (2013.01);
Abstract
Antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region. A composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer.