The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2016
Filed:
Jun. 06, 2014
Applicant:
Sarepta Therapeutics, Inc., Corvallis, OR (US);
Inventors:
Gunnar J. Hanson, Bothell, WA (US);
Alexander Charles Rudolph, Snoqualmie, WA (US);
Bao Zhong Cai, Corvallis, OR (US);
Ming Zhou, Coppell, TX (US);
Dwight D. Weller, Corvallis, OR (US);
Assignee:
Sarepta Therapeutics, Inc., Corvallis, OR (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6544 (2006.01); C07F 9/22 (2006.01); C07F 9/26 (2006.01); C07D 265/30 (2006.01); C07D 295/108 (2006.01); C07F 9/59 (2006.01); C07F 9/6561 (2006.01); C07F 9/6584 (2006.01); C07F 9/572 (2006.01); C07F 9/6558 (2006.01); C07H 21/00 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07F 9/6544 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); C07D 265/30 (2013.01); C07D 295/108 (2013.01); C07F 9/222 (2013.01); C07F 9/26 (2013.01); C07F 9/5727 (2013.01); C07F 9/598 (2013.01); C07F 9/6561 (2013.01); C07F 9/65583 (2013.01); C07F 9/65846 (2013.01); C07H 21/00 (2013.01);
Abstract
Oligonucleotide analogs comprising modified intersubunit linkages and/or modified 3' and/or 5′-end groups are provided. The disclosed compounds are useful for the treatment of diseases where inhibition of protein expression or correction of aberrant mRNA splice products produces beneficial therapeutic effects.