The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2016
Filed:
Sep. 27, 2013
Applicant:
Portola Pharmaceuticals, Inc., South San Francisco, CA (US);
Inventors:
Anjali Pandey, Fremont, CA (US);
Yonghong Song, Foster City, CA (US);
Qing Xu, Foster City, CA (US);
Assignee:
PORTOLA PHARMACEUTICALS, INC., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5365 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01);
Abstract
Provided are bicyclic oxa-lactam compounds of formula I: and pharmaceutically acceptable salts thereof which are inhibitors of JAK/Syk kinase. The present disclosure is also directed to intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibiting JAK/Syk kinase activity, and methods for treating conditions mediated at least in part by JAK/Syk kinase activity.