The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2016
Filed:
Aug. 20, 2014
Applicant:
Radiant Pharma & Tech. Co., Ltd., Zhenjiang, Jiangsu, CN;
Inventors:
Yingjian Hu, Zhenjiang, CN;
Zhibin Luo, Zhenjiang, CN;
Yanhong Zhang, Zhenjiang, CN;
Li Han, Zhenjiang, CN;
Yun Wang, Zhenjiang, CN;
Hongfei Lu, Zhenjiang, CN;
Assignee:
Radiant Pharma & Tech. Co., Ltd., Zhenjiang, Jiangsu Province, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 231/56 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 231/56 (2013.01);
Abstract
The present invention relates to naphthylurea derivatives. Such substances can significantly inhibit VEGFR2 and PDGFR-β receptor tyrosine kinase phosphorylation at nanomolar concentration levels. It is a novel type of tyrosine kinase inhibitors which can be used in the treatment of tyrosine kinase-mediated diseases or symptoms such as malignancies and ocular diseases accompanied with pathologic neovascularization.