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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9469623 B1

PDFFull Text
Date of Patent:
Oct. 18, 2016

Filed:

Feb. 06, 2015

Preparation method for optically active bicyclic gamma-amino acid compound

Applicant:

Daiichi Sankyo Company, Limited, Tokyo, JP;

Inventors:

Yoshitaka Nakamura, Kanagawa, JP;

Kazutoshi Ukai, Kanagawa, JP;

Takafumi Kitawaki, Kanagawa, JP;

Takumi Nakajima, Kanagawa, JP;

Yutaka Kitagawa, Kanagawa, JP;

Yukito Furuya, Tokyo, JP;

Makoto Imai, Kanagawa, JP;

Eiji Numagami, Kanagawa, JP;

Masakazu Wakayama, Kanagawa, JP;

Ayako Saito, Kanagawa, JP;

Assignee:

Daiichi Sankyo Company, Limited, Tokyo, JP;

Attorney:

Dorsey & Whitney LLP

Primary Examiner:

Samantha Shterengarts

Assistant Examiner:

Matt Mauro

Int. Cl.
CPC ...
C07C 67/343 (2006.01); C07C 211/27 (2006.01); C07C 201/16 (2006.01); C07C 253/34 (2006.01); C07C 253/30 (2006.01); C07C 227/42 (2006.01); C07C 253/10 (2006.01); C07D 319/06 (2006.01); C07C 255/47 (2006.01); C07C 201/12 (2006.01); C07C 205/50 (2006.01); C07C 229/32 (2006.01); C07C 227/04 (2006.01); C07C 67/00 (2006.01); C07C 69/608 (2006.01); C07C 253/00 (2006.01);
U.S. Cl.
CPC ...
C07D 319/06 (2013.01); C07C 67/00 (2013.01); C07C 67/343 (2013.01); C07C 69/608 (2013.01); C07C 201/12 (2013.01); C07C 201/16 (2013.01); C07C 205/50 (2013.01); C07C 211/27 (2013.01); C07C 227/04 (2013.01); C07C 227/42 (2013.01); C07C 229/32 (2013.01); C07C 253/00 (2013.01); C07C 253/10 (2013.01); C07C 253/30 (2013.01); C07C 253/34 (2013.01); C07C 255/47 (2013.01); C07B 2200/07 (2013.01); C07C 2102/20 (2013.01);
Abstract

An object of the present invention is to provide an optically active bicyclic γ-amino acid derivative in a high purity. The object can be attained by a mixture of compounds represented by the general formulas (I) and (I'), or a method for producing a compound represented by the general formula (VII) or a salt thereof via the compound (I): wherein Rand Reach represent a C1-6 alkyl group or the like; and Rrepresents a cyano group or the like,

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