The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2016
Filed:
Oct. 25, 2012
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Sam W. Lee, Newton Center, MA (US);
Anna I. Mandinova, Newton, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 317/48 (2006.01); C07C 317/32 (2006.01); A61K 31/18 (2006.01);
U.S. Cl.
CPC ...
C07C 317/48 (2013.01); A61K 31/18 (2013.01); C07C 317/32 (2013.01);
Abstract
This disclosure relates to inhibitors of the Wni pathway, and compositions comprising the same, as well as to their use in the treatment of disorders characterized by the activation of Writ pathway signaling (e.g., cancer), as well as to the modulation of cellular events mediated by VVnt pathway signaling.