The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2016
Filed:
Mar. 28, 2012
Applicants:
Ann Debunne, De Pinte, BE;
Veronique DE Brabandere, Gent, BE;
Inventors:
Ann Debunne, De Pinte, BE;
Veronique De Brabandere, Gent, BE;
Assignee:
Ablynx N.V., Zwijnaarde, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/44 (2006.01); A61K 9/16 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/44 (2013.01); A61K 9/1635 (2013.01); A61K 9/1652 (2013.01); A61K 9/1676 (2013.01); A61K 39/39591 (2013.01); C07K 16/00 (2013.01); C07K 2317/22 (2013.01); C07K 2317/569 (2013.01);
Abstract
Methods for preparing solid formulations of immunoglobulin single variable domains are provided. The methods are based on contacting solid carrier(s) with a liquid comprising the immunoglobulin single variable domains, e.g. by spraying the liquid onto the solid carrier(s), to cause granulation or coating of the carrier(s). During contacting the carrier is agitated, e.g. in a fluid bed, and the mixture of carrier and liquid is exposed to heat, e.g. a heated air stream, to evaporate the liquid.