The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2016

Filed:

Mar. 13, 2015
Applicant:

Pfizer Inc, New York, NY (US);

Inventors:

Joseph John Binder, San Diego, CA (US);

Helen Kim Cho, San Diego, CA (US);

Michael Robert Dermyer, Carlsbad, CA (US);

Karin Ute Jooss, San Diego, CA (US);

Brian Gregory Pierce, Wayland, MA (US);

Joyce Tsi Tan, Chapel Hill, NC (US);

Van To Tsai, San Diego, CA (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07H 21/04 (2006.01); A61K 39/39 (2006.01); A61K 39/395 (2006.01); C12N 9/48 (2006.01); A61K 31/404 (2006.01); C07K 14/47 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 31/404 (2013.01); A61K 39/39 (2013.01); A61K 39/3955 (2013.01); C07K 14/4748 (2013.01); C12N 9/485 (2013.01); C12N 9/6445 (2013.01); C12Y 304/17021 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55561 (2013.01);
Abstract

The present disclosure provides (a) isolated immunogenic PAA polypeptides; (b) isolated nucleic acid molecules encoding immunogenic PAA polypeptides; (c) vaccine compositions comprising an immunogenic PAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic PAA polypeptide; (d) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions; and (e) vaccine-based immunotherapy regimens which involve co-administration of a vaccine in combination with an immune-suppressive-cell inhibitor and an immune-effector-cell enhancer.


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