logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9468635 B1

PDFFull Text
Date of Patent:
Oct. 18, 2016

Filed:

Jan. 07, 2015

Fused ring compound for use as mineralocorticoid receptor antagonist

Applicant:

Kbp Biosciences Co., Ltd., Jinan, Shandong Province, CN;

Inventors:

Zhenhua Huang, Jinan, CN;

Jinyuan Wang, Jinan, CN;

Dedong Zhang, Jinan, CN;

Assignee:

KBP BIOSCIENCES CO., Ltd., Jinan, Shandong Province, CN;

Attorney:

Kilpatrick Townsend & Stockton LLP

Primary Examiner:

Kendra D Carter

Int. Cl.
CPC ...
A61K 31/416 (2006.01); A61K 31/381 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61K 31/4745 (2006.01); A61K 31/40 (2006.01); A61K 31/401 (2006.01); A61K 31/407 (2006.01); A61K 31/417 (2006.01); A61K 31/437 (2006.01); A61K 31/4985 (2006.01); A61K 31/517 (2006.01); A61K 31/5365 (2006.01); A61K 45/06 (2006.01); A61K 31/4025 (2006.01); A61K 38/17 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61K 31/381 (2013.01); A61K 31/40 (2013.01); A61K 31/401 (2013.01); A61K 31/407 (2013.01); A61K 31/4025 (2013.01); A61K 31/417 (2013.01); A61K 31/437 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); A61K 31/517 (2013.01); A61K 31/5365 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 38/1709 (2013.01); A61K 45/06 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention belongs to the technical field of medicine, relating in particular to: a fused ring compound as represented by Formula (I) for use as a mineralocorticoid receptor antagonist, a pharmaceutically acceptable salt thereof, and an isomer thereof; a preparation method for these compounds; a pharmaceutical preparation containing these compounds; and an application of these compounds, the pharmaceutically acceptable salt thereof, or the isomers thereof in the preparation of medicants for the treatment and/or prevention of kidney injury, cardiovascular diseases such as hypertension, and/or endocrine disease. The definitions of X, Y, Y, Y, R, R, R, R, R, R, Cy and n are as presented in the description.

Find Patent Forward Citations

Loading…