The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2016
Filed:
Oct. 04, 2012
Baxalta Gmbh, Glattpark (Opfikon), CH;
Baxalta Incorporated, Bannockburn, IL (US);
Randolf J. Kerschbaumer, Klosterneuburg, AT;
Dirk Voelkel, Vienna, AT;
Gerhard Antoine, Gross-Enzersdorf, AT;
Friedrich Scheiflinger, Vienna, AT;
Geert C. Mudde, Breitenfurt, AT;
Baxalta Incorporated, Bannockburn, IL (US);
Baxalta GmbH, Glattpark (Opfikon), CH;
Abstract
The present invention is concerned with the specific and highly sensitive detection of specific CHO-MIF (macrophage migration inhibitory factor from Chinese Ovarian Hamster cell line) complexes in the production of anti-MIF antibodies. The present invention is further concerned with the provision of specific antibodies which can be used for a CHO-MIF detection method. The present invention is also concerned with a CHO MIF knockout cell line and use thereof. The present invention also provides preparations obtained from recombinant production in CHO cell lines which are essentially free of CHO-MIF.