The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2016
Filed:
Jan. 10, 2014
Applicant:
Anticancer, Inc., San Diego, CA (US);
Inventors:
Yuying Tan, San Diego, CA (US);
Shukuan Li, San Diego, AZ (US);
Assignee:
AntiCancer, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); C12Q 1/527 (2006.01); C07F 9/58 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/527 (2013.01); C07F 9/582 (2013.01);
Abstract
A composition, method and kit for performing a two-reagent enzymatic homocysteine assay, wherein a single homocysteinase enzyme and a Schiff-based conjugate of N,N-dibutyl-p-phenyldiamine (DBPDA) with pyridoxal 5'-phosphate (PLP) are used to measure total homocysteine in plasma or serum. The assay measures a chromophore reaction product of HS and the DBPDA released from the Schiff-base conjugate in the presence of a Fecontaining compound. The resulting chromophore may be measured absorbance or fluorescence spectrophotometry.