The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2016

Filed:

Nov. 18, 2014
Applicant:

Anthrogenesis Corporation, Warren, NJ (US);

Inventors:

Robert J. Hariri, Bernardsville, NJ (US);

Mohammad A. Heidaran, Potomac, MD (US);

Stephen Jasko, Rutherford, NJ (US);

Lin Kang, Edison, NJ (US);

Eric Law, East Brunswick, NJ (US);

Ajai Pal, Bridgewater, NJ (US);

Bhavani Stout, Lebanon, NJ (US);

Vanessa Voskinarian-Berse, Millington, NJ (US);

Andrew Zeitlin, Basking Ridge, NJ (US);

Xiaokui Zhang, Livingston, NJ (US);

Assignee:

Anthrogenesis Corporation, Warren, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A01N 65/00 (2009.01); C12N 5/0783 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0646 (2013.01); A61K 2035/124 (2013.01); C12N 2500/05 (2013.01); C12N 2500/25 (2013.01); C12N 2500/33 (2013.01); C12N 2500/36 (2013.01); C12N 2500/38 (2013.01); C12N 2500/44 (2013.01); C12N 2500/46 (2013.01); C12N 2501/125 (2013.01); C12N 2501/145 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2303 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/26 (2013.01); C12N 2501/59 (2013.01); C12N 2501/91 (2013.01); C12N 2501/998 (2013.01); C12N 2506/11 (2013.01);
Abstract

Provided herein are methods of producing natural killer cells using a two-step expansion and differentiation method. Also provided herein are methods of suppressing tumor cell proliferation, of treating individuals having cancer or a viral infection, comprising administering the NK cells produced by the method to an individual having the cancer or viral infection.


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