The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2016

Filed:

Oct. 24, 2007
Applicants:

Cristina Carreño Serraïma, Gavá-Barcelona, ES;

Berta Ponsati Obiols, San Quintí de Mediona-Barcelona, ES;

Wim Van Den Nest, Gavá-Barcelona, ES;

Jimena Fernandez Carneado, San Quintí de Mediona-Barcelona, ES;

Antonio Ferrer Montiel, San Quintí de Mediona-Barcelona, ES;

Juan Cebrian Puche, Gavá-Barcelona, ES;

Nuria Almiñana Domenech, Gavá-Barcelona, ES;

Inventors:

Cristina Carreño Serraïma, Gavá-Barcelona, ES;

Berta Ponsati Obiols, San Quintí de Mediona-Barcelona, ES;

Wim Van Den Nest, Gavá-Barcelona, ES;

Jimena Fernandez Carneado, San Quintí de Mediona-Barcelona, ES;

Antonio Ferrer Montiel, San Quintí de Mediona-Barcelona, ES;

Juan Cebrian Puche, Gavá-Barcelona, ES;

Nuria Almiñana Domenech, Gavá-Barcelona, ES;

Assignee:

BCN PEPTIDES S.A., San Quinti De Mediona, Barcelona, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/705 (2006.01); A61K 8/14 (2006.01); A61K 8/64 (2006.01); A61Q 19/00 (2006.01); A61Q 19/10 (2006.01); A61Q 19/08 (2006.01);
U.S. Cl.
CPC ...
C07K 14/705 (2013.01); A61K 8/14 (2013.01); A61K 8/64 (2013.01); A61Q 19/00 (2013.01); A61Q 19/10 (2013.01); A61K 38/00 (2013.01); A61Q 19/08 (2013.01);
Abstract

The invention relates to peptides of general formula (I):R-AA-R  (I)which can regulate neuronal exocytosis, their stereoisomers and racemic or non-racemic mixtures thereof, and the cosmetically or pharmaceutically acceptable salts thereof, wherein AA is a sequence of 3 to 40 adjacent amino acids contained in the amino acid sequence of the SNAP-25 protein, Ris selected from the group consisting of H or alkyl, aryl, aralkyl or acyl group; and Ris selected from the group consisting of amino, hydroxyl or thiol, substituted or non-substituted with aliphatic or cyclic groups, with the condition that when Ris H or acetyl, Ris not non-substituted amino, hydroxyl or thiol. The invention also relates to a method of obtaining such peptides, cosmetic or pharmaceutical compositions containing them and their use to treat those conditions requiring neuronal exocytosis regulation, preferably for treating the skin.


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