The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2016
Filed:
Jul. 19, 2013
Applicant:
Altor Bioscience Corporation, Miramar, FL (US);
Inventors:
Hing C. Wong, Weston, FL (US);
Peter Rhode, Miami, FL (US);
Xiaoyun Zhu, Miami, FL (US);
Kai-ping Han, Miramar, FL (US);
Assignee:
Altor Bioscience Corporation, Miramar, FL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/54 (2006.01); C07K 14/705 (2006.01); C07K 19/00 (2006.01); C07K 16/18 (2006.01); C12N 15/62 (2006.01); C12N 15/09 (2006.01); C07K 14/715 (2006.01); A61K 47/48 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01); G01N 33/569 (2006.01); C07K 14/435 (2006.01); C07K 14/47 (2006.01); C07K 16/24 (2006.01); C12N 15/24 (2006.01); A61K 38/00 (2006.01); C12P 21/00 (2006.01); A61K 38/20 (2006.01);
U.S. Cl.
CPC ...
C07K 14/5443 (2013.01); A61K 47/48269 (2013.01); A61K 47/48276 (2013.01); A61K 47/48423 (2013.01); C07K 14/7051 (2013.01); C07K 14/7155 (2013.01); C07K 16/28 (2013.01); C12N 15/09 (2013.01); C12N 15/62 (2013.01); G01N 33/56977 (2013.01); A61K 38/00 (2013.01); A61K 38/2086 (2013.01); C07K 16/18 (2013.01); C07K 2319/00 (2013.01); C07K 2319/31 (2013.01); C07K 2319/33 (2013.01); C07K 2319/74 (2013.01); C07K 2319/75 (2013.01); C12P 21/00 (2013.01);
Abstract
The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making the such proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention.