The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2016

Filed:

Oct. 02, 2014
Applicant:

Astex Therapeutics Ltd, Cambridge, GB;

Inventors:

Gordon Saxty, Cambridge, GB;

Christopher William Murray, Cambridge, GB;

Valerio Berdini, Cambridge, GB;

Gilbert Ebai Besong, Bad Duerkheim, DE;

Christopher Charles Frederick Hamlett, Cambridge, GB;

Christopher Norbert Johnson, Cambridge, GB;

Steven John Woodhead, San Diego, CA (US);

Michael Reader, Bishop's Stortford, GB;

David Charles Rees, Cambridge, GB;

Laurence Anne Mevellec, Louviers, FR;

Patrick René Angibaud, Fontaine-Bellenger, FR;

Eddy Jean Edgard Freyne, Rumst, BE;

Tom Cornelis Hortense Govaerts, Betekom, BE;

Johan Erwin Edmond Weerts, Beerse, BE;

Timothy Pietro Suren Perera, Geel, BE;

Ronaldus Arnodus Hendrika Joseph Gilissen, Kasterlee, BE;

Berthold Wroblowski, Vosselaar, BE;

Jean Fernand Armand Lacrampe, Le Mesnil-Esnard, FR;

Alexandra Papanikos, Antwerp, BE;

Olivier Alexis Georges Querolle, Evreux, FR;

Elisabeth Thérèse Jeanne Pasquier, Le Neubourg, FR;

Isabelle Noëlle Constance Pilatte, Louviers, FR;

Pascal Ghislain André Bonnet, Berchem, BE;

Werner Constant Johan Embrechts, Beerse, BE;

Rhalid Akkari, Vacquieres, FR;

Lieven Meerpoel, Beerse, BE;

Assignee:

ASTEX THERAPEUTICS LTD, Cambridge, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 231/10 (2006.01); C07D 231/12 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 487/08 (2006.01); A61K 31/498 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 491/113 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61K 31/498 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 487/08 (2013.01); C07D 491/113 (2013.01);
Abstract

The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.


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