The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2016
Filed:
Mar. 15, 2013
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);
The University of Kansas, Lawrence, KS (US);
Juan Jose Marugan, Gaithersburg, MD (US);
Wei Zheng, Potomac, MD (US);
Samarjit Patnaik, Gaithersburg, MD (US);
Noel Southall, Potomac, MD (US);
Ellen Sidransky, Bethesda, MD (US);
Ehud Goldin, Rockville, MD (US);
Wendy Westbroek, Rockville, MD (US);
Elma Aflaki, Rockville, MD (US);
Steven Andrew Rogers, Lawrence, KS (US);
Frank John Schoenen, Lawrence, KS (US);
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, Washington, DC (US);
THE UNIVERSITY OF KANSAS, Lawrence, KS (US);
Abstract
Compounds of Formula (I) and the pharmaceutically acceptable salts thereof are disclosed. The variables. R-R, m, n, o, and p are disclosed herein. The compounds are useful for treating Gaucher disease and inhibiting the onset of Gaucher disease symptoms in a patient having a GBA gene mutation and for treating Parkinson's disease. Pharmaceutical compositions containing compounds of Formula (I) and methods of treatment comprising administering compounds of Formula (I) are also disclosed.