The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2016
Filed:
Jul. 17, 2008
Applicants:
Massimo Bigio, Siena, IT;
Giovanni Averani, Siena, IT;
Francesco Norelli, Siena, IT;
Francesco Berti, Siena, IT;
Cinzia Bellucci, Siena, IT;
Inventors:
Massimo Bigio, Siena, IT;
Giovanni Averani, Siena, IT;
Francesco Norelli, Siena, IT;
Francesco Berti, Siena, IT;
Cinzia Bellucci, Siena, IT;
Assignee:
GlaxoSmithKline Biologicals SA, Rixensart, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01); C07K 1/14 (2006.01); C07K 1/16 (2006.01); A61K 47/48 (2006.01); A61K 39/09 (2006.01); B01D 15/38 (2006.01); B01J 20/04 (2006.01); A61K 39/095 (2006.01); A61K 39/085 (2006.01); A61K 39/112 (2006.01); A61K 39/02 (2006.01); A61K 39/104 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48261 (2013.01); A61K 39/092 (2013.01); A61K 47/4833 (2013.01); A61K 47/48246 (2013.01); A61K 47/48269 (2013.01); B01D 15/3847 (2013.01); B01J 20/048 (2013.01); C07K 1/165 (2013.01); A61K 39/0275 (2013.01); A61K 39/085 (2013.01); A61K 39/095 (2013.01); A61K 39/104 (2013.01); A61K 39/107 (2013.01); A61K 2039/6037 (2013.01);
Abstract
This application relates to methods for the purification of saccharide antigen-carrier protein conjugates. In particular, the invention provides a method for purifying saccharide antigen-carrier protein conjugates from free carrier protein, such as CRM1 97, using hydroxyapatite. The invention further relates to methods of preparing vaccines, using this method.