The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2016
Filed:
Dec. 14, 2007
Applicants:
David S. Eisenberg, Los Angeles, CA (US);
Melinda Balbirnie, Santa Monica, CA (US);
Inventors:
David S. Eisenberg, Los Angeles, CA (US);
Melinda Balbirnie, Santa Monica, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/14 (2006.01); A61M 1/34 (2006.01); A61K 31/65 (2006.01); A61M 1/30 (2006.01);
U.S. Cl.
CPC ...
A61K 31/65 (2013.01); A61M 1/30 (2013.01); A61M 1/3486 (2014.02);
Abstract
Methods for disrupting amyloid fibrils in a subject, comprising combining an effective amount of a β-2 microglobulin fibril disrupting compound with a medium associated with the subject, are disclosed. The invention also relates to combining the β-2 microglobulin fibril disrupting compound ex vivo with the blood during dialysis treatment of an animal. It also relates to methods for determining which compounds are effective at disrupting amyloid fibrils in a medium.