The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2016

Filed:

Jun. 27, 2014
Applicants:

Nippon Chemiphar Co., Ltd., Tokyo, JP;

Senju Pharmaceutical Co., Ltd., Osaka, JP;

Inventors:

Yoshikuni Nakamura, Hyogo, JP;

Ikuko Hanano, Hyogo, JP;

Jun Inoue, Woodland Hills, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/421 (2006.01); A61K 31/427 (2006.01); A61K 31/426 (2006.01); C07D 263/32 (2006.01); C07D 277/24 (2006.01); C07D 417/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/427 (2013.01); A61K 31/421 (2013.01); A61K 31/426 (2013.01); C07D 263/32 (2013.01); C07D 277/24 (2013.01); C07D 417/06 (2013.01);
Abstract

A preparation containing [3-[2-[4-isopropyl-2-(4-trifluoromethyl)phenyl-5-thiazolyl]ethyl]-5-methyl-1,2-benzisoxazol-6-yl]oxyacetic acid, [4-[3-[2-(4-trifluoromethyl)phenyl-4-isopropyl-5-thiazolyl]propionyl]-2-methylphenoxy]acetic acid or [4-[3-[2-(2-hydroxy-4-chlorophenyl)-5-isopropyl-4-oxazolyl]propionyl]-2-methylphenoxy]acetic acid, or a pharmacologically acceptable salt thereof as an active ingredient is used as an agent for promoting proliferation of meibomian gland epithelial cells or corneal epithelial cells, as well as a therapeutic agent for ocular diseases such as meibomian gland dysfunction, dry eye and the like.


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