The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
Dec. 20, 2012
Applicant:
Charis Eng, Cleveland Heights, OH (US);
Inventor:
Charis Eng, Cleveland Heights, OH (US);
Assignee:
The Cleveland Clinic Foundation, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/158 (2013.01);
Abstract
A method of diagnosing Cowden syndrome (CS) and Cowden-like Syndrome (CLS) is described. The method includes diagnosing CS and CLS in a subject by identifying a decrease in expression of the KILLIN gene, or by identifying hypermethylation of the KILLIN promoter region. Kits for diagnosing CS and CLS by identifying subjects having KILLIN promoter region hypermethylation and primers specific for a methylated KILLIN promoter region are also described.
Eng, Charis. (2016). Diagnosis of cowden and cowden-like syndrome by detection of decreased killin expression (U.S. Patent No. 9458505). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9458505
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile