The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
Aug. 14, 2014
Applicants:
Ping Jiang, San Diego, CA (US);
H. Michael Shepard, San Diego, CA (US);
Lei Huang, San Diego, CA (US);
Inventors:
Ping Jiang, San Diego, CA (US);
H. Michael Shepard, San Diego, CA (US);
Lei Huang, San Diego, CA (US);
Assignee:
Halozyme, Inc., San Diego, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/81 (2006.01); C12N 9/26 (2006.01); A61K 38/47 (2006.01); G01N 33/574 (2006.01); G01N 33/566 (2006.01); G01N 33/68 (2006.01); A61K 47/10 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2474 (2013.01); A61K 38/47 (2013.01); A61K 47/10 (2013.01); C07K 14/47 (2013.01); G01N 33/566 (2013.01); G01N 33/574 (2013.01); G01N 33/57488 (2013.01); G01N 33/6893 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/735 (2013.01); G01N 2333/705 (2013.01); G01N 2400/40 (2013.01); G01N 2800/52 (2013.01);
Abstract
Methods and diagnostic agents for identification of subjects for cancer treatment with an anti-hyaluronan agent, such as a hyaluronan-degrading enzyme, are provided. Diagnostic agents for the detection and quantification of hyaluronan in a biological sample and monitoring cancer treatment with an anti-hyaluronan agent, for example a hyaluronan-degrading enzyme, are provided. Combinations and kits for use in practicing the methods also are provided.