The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
May. 16, 2014
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventor:
Shigemi Matsuyama, Cleveland, OH (US);
Assignee:
Case Western Reserve University, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/04 (2006.01); C07K 14/715 (2006.01); C12N 5/0793 (2010.01); A61K 38/08 (2006.01); A61K 38/07 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0619 (2013.01); A61K 38/07 (2013.01); A61K 38/08 (2013.01); C07K 14/7156 (2013.01); C07K 16/2866 (2013.01); C07K 2317/34 (2013.01); C07K 2319/01 (2013.01);
Abstract
A method of inhibiting β-amyloid (Aβ) induced neuronal cell death includes administering to a neuronal cell exposed to a neurotoxic amount of Aβ a therapeutically effective amount of cell penetrating peptide (CPP). The CPP has an amino acid sequence that has at least 80% sequence identity to about 5 to about 41 consecutive amino acids of SEQ ID NO: 1.