The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
Oct. 16, 2014
Applicant:
Affitech Research As, Oslo, NO;
Inventors:
Urs Beat Hagemann, Oslo, NO;
Remko Albert Griep, Slemmestad, NO;
Herald Reiersen, Sofiemyr, NO;
Sergej Michailovi{hacek over (c)} Kiprijanov, Oslo, NO;
Assignee:
Cancer Research Technology Limited, London, GB;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 5/10 (2006.01); C12N 7/01 (2006.01); C12N 15/63 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/41 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); G01N 2333/7158 (2013.01);
Abstract
The present invention provides antibodies which bind to an epitope in the extracellular domain of human CC chemokine receptor 4 (CCR4) and which are capable of inhibiting the binding of macrophage-derived chemokine (MDC) and/or thymus and activation regulated chemokine (TARC) to CCR4. Also provided are inter alia immunoconjugates and compositions comprising such antibodies and methods and uses involving such antibodies, particularly in the medical and diagnostic fields.