The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
Jun. 23, 2009
Markus Kalesse, Burgdorf, DE;
Nisar Malek, Hannover, DE;
Ronald Frank, Meine, DE;
Tobias Brodmann, Hannover, DE;
Leila Bülow, Hannover, DE;
Andreas Rentsch, Hannover, DE;
Anna-katharina Girbig, Hannover, DE;
Ulrike Eggert, Hannover, DE;
Markus Kalesse, Burgdorf, DE;
Nisar Malek, Hannover, DE;
Ronald Frank, Meine, DE;
Tobias Brodmann, Hannover, DE;
Leila Bülow, Hannover, DE;
Andreas Rentsch, Hannover, DE;
Anna-Katharina Girbig, Hannover, DE;
Ulrike Eggert, Hannover, DE;
Gottfried Wilhelm Leibniz Universität Hannover, Hannover, DE;
Medizinische Hochschule Hannover, Hannover, DE;
Helmholtz-Zentrum für Infektionsforschung GmbH, Braunschweig, DE;
Abstract
The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof, for a treatment in a variety of conditions, such as the induction of immunotolerance, autoimmune diseases, bacterial infections, and proliferative diseases, such as cancers.