The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
Jun. 12, 2013
Shire Orphan Therapies Gmbh, Berlin, DE;
Frank Osterkamp, Berlin, DE;
Heiko Hawlisch, Berlin, DE;
Gerd Hummel, Berlin, DE;
Tobias Knaute, Berlin, DE;
Ulf Reimer, Berlin, DE;
Ulrich Reineke, Berlin, DE;
Bernadett Simon, Bonn, DE;
Uwe Richter, Berlin, DE;
Edgar Specker, Berlin, DE;
Markus Woischnik, Berlin, DE;
Mark R. Hellberg, Arlington, TX (US);
Shire Orphan Therapies GmbH, Berlin, DE;
Abstract
Disclosed are cyclic, peptide-based novel compounds having NPR-B agonistic activity. Preferred compounds are cyclic peptides containing conventional or non-conventional L- or D-amino acid residues connected to one another via peptide bonds. In some embodiments, provided herein are a cyclic peptide compound with a ring size that is significantly reduced as compared to known NPR-B agonists, such as CNP.