The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
Feb. 21, 2013
Applicant:
Sanford-burnham Medical Research Institute, La Jolla, CA (US);
Inventors:
Anthony B. Pinkerton, La Jolla, CA (US);
Russell Dahl, La Jolla, CA (US);
Nicholas D. P. Cosford, La Jolla, CA (US);
Jose Luis Millan, La Jolla, CA (US);
Assignee:
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE, La Jolla, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 213/76 (2006.01); C07D 215/38 (2006.01); C07D 409/04 (2006.01); C07D 405/04 (2006.01); C07D 409/12 (2006.01); C07D 417/04 (2006.01); C07D 405/12 (2006.01); C07D 401/12 (2006.01); C07D 401/04 (2006.01); A61K 31/44 (2006.01); A61K 31/50 (2006.01); C07D 213/80 (2006.01); C07D 213/82 (2006.01); C07D 231/42 (2006.01); C07D 333/36 (2006.01); C07D 237/20 (2006.01); C07D 239/69 (2006.01); C07D 241/22 (2006.01); C07D 261/16 (2006.01); C07D 263/50 (2006.01); C07D 271/113 (2006.01); C07D 277/52 (2006.01); C07D 285/135 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); A61K 31/44 (2013.01); A61K 31/50 (2013.01); C07D 213/76 (2013.01); C07D 213/80 (2013.01); C07D 213/82 (2013.01); C07D 215/38 (2013.01); C07D 231/42 (2013.01); C07D 237/20 (2013.01); C07D 239/69 (2013.01); C07D 241/22 (2013.01); C07D 261/16 (2013.01); C07D 263/50 (2013.01); C07D 271/113 (2013.01); C07D 277/52 (2013.01); C07D 285/135 (2013.01); C07D 333/36 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 409/04 (2013.01); C07D 409/12 (2013.01);
Abstract
Described herein are compounds that modulate the activity of TNAP. In some embodiments, the compounds described herein inhibit TNAP. In certain embodiments, the compounds described herein are useful in the treatment of conditions associated with hyper-mineralization.