The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2016

Filed:

May. 08, 2014
Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Evangelos Aktoudianakis, San Mateo, CA (US);

Gregory Chin, San Francisco, CA (US);

Britton Kenneth Corkey, Redwood City, CA (US);

Jinfa Du, Redwood City, CA (US);

Kristyna Elbel, South San Francisco, CA (US);

Robert H. Jiang, Cupertino, CA (US);

Tetsuya Kobayashi, Pleasanton, CA (US);

Rick Lee, Livermore, CA (US);

Ruben Martinez, San Diego, CA (US);

Samuel E. Metobo, Newark, CA (US);

Michael Mish, Foster City, CA (US);

Manuel Munoz, San Mateo, CA (US);

Sophie Shevick, San Francisco, CA (US);

David Sperandio, Palo Alto, CA (US);

Hai Yang, San Mateo, CA (US);

Jeff Zablocki, Los Altos, CA (US);

Assignee:

Gilead Sciences, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 417/14 (2006.01); C07D 413/14 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract

This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R, R, R, R, R, R, R, and Rare described herein.


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