The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2016

Filed:

Sep. 29, 2015
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Forschungsverbund Berlin E.v., Berlin-Adlershof, DE;

Inventors:

Marvin C. Gershengorn, Washington, DC (US);

Susanne Neumann, Bethesda, MD (US);

Bruce M. Raaka, Rockville, MD (US);

Craig J. Thomas, Gaithersburg, MD (US);

James Inglese, Bethesda, MD (US);

Noel T. Southall, Chevy Chase, MD (US);

Steven Titus, Elkridge, MD (US);

Wei Zheng, Potomac, MD (US);

Wenwei Huang, Rockville, MD (US);

Gerd Krause, Berlin, DE;

Gunnar Kleinau, Berlin, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); C07D 239/88 (2006.01); C07D 217/24 (2006.01); A61K 31/47 (2006.01); A61P 35/00 (2006.01); A61K 31/167 (2006.01); A61K 31/517 (2006.01); C07C 233/01 (2006.01); C07D 405/06 (2006.01); C07D 239/91 (2006.01); C07D 401/06 (2006.01); C07D 405/14 (2006.01); C07D 487/04 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
C07D 405/06 (2013.01); A61K 31/517 (2013.01); A61K 49/0004 (2013.01); A61K 51/00 (2013.01); C07D 239/91 (2013.01); C07D 401/06 (2013.01); C07D 405/14 (2013.01); C07D 487/04 (2013.01);
Abstract

Disclosed are oxo-hydroquinazolines that are useful as selective TSHR agonists. The compounds may be used for detecting or treating thyroid cancer, or treating a bone degenerative disorder.


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