The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
May. 08, 2014
Applicant:
Eternity Bioscience Inc., Cranbury, NJ (US);
Inventors:
Dong Liu, Bridgewater, NJ (US);
Minsheng Zhang, Warren, NJ (US);
Assignee:
Eternity Bioscience Inc., Cranbury, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01); A61K 31/53 (2006.01); A61K 31/443 (2006.01); A61K 31/444 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 417/14 (2013.01); A61K 31/443 (2013.01); A61K 31/444 (2013.01); A61K 31/506 (2013.01); A61K 31/53 (2013.01);
Abstract
The present disclosure provides novel furanone compounds, or pharmaceutically acceptable salts, solvates or prodrugs thereof, as Raf kinase, especially BRAF kinase, inhibitors, which are useful therapeutic agents for treatment of Raf kinase related diseases or disorders, such as melanomas, cancers, and leukemia. The disclosure also provides methods and processes for preparing these novel furanone compounds, pharmaceutical compositions containing these furanone compounds, and methods of treatment using these furanone compounds.