The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2016

Filed:

Nov. 08, 2012
Applicants:

Young-sup Yoon, Atlanta, GA (US);

Xiaodong Cheng, Decatur, GA (US);

Ji Woong Han, Decatur, GA (US);

Antonello Mai, Rome, IT;

Inventors:

Young-Sup Yoon, Atlanta, GA (US);

Xiaodong Cheng, Decatur, GA (US);

Ji Woong Han, Decatur, GA (US);

Antonello Mai, Rome, IT;

Assignee:

Emory University, Atlanta, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/72 (2006.01); C07D 211/08 (2006.01); C07D 211/56 (2006.01); C07D 401/12 (2006.01); A61K 31/517 (2006.01); A61K 45/06 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01);
Abstract

This disclosure relates to compounds, compositions and methods of epigenetically transforming cells. In certain embodiments, the disclosure relates to methods of generating epigenetically altered cells comprising mixing isolated cells with compositions disclosed herein under conditions such that epigenetically altered cells are formed. In certain embodiments, the disclosure contemplates inducing cells, such as adult somatic cells or cells that are not naturally pluripotent, into cells with chemically induce pluripotency. In certain embodiments, the disclosure contemplates certain compounds disclosed herein, compounds disclosed herein optionally substituted with one or more substituents, derivatives, or salts thereof, for these purposes.


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