The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2016

Filed:

Oct. 06, 2011
Applicants:

Heejin Lee, Arlington, MA (US);

Hong Linh Ho Duc, Watertown, MA (US);

Inventors:

Heejin Lee, Arlington, MA (US);

Hong Linh Ho Duc, Watertown, MA (US);

Assignee:

TARIS Biomedical LLC, Lexington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 31/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61M 31/002 (2013.01); A61K 9/0034 (2013.01); A61K 9/0065 (2013.01); A61M 2210/1085 (2013.01);
Abstract

Implantable devices and methods for controlled drug delivery are provided. The device includes a device structure deformable between a retention shape and a low profile shape for deployment in the bladder of a patient and has a drug reservoir lumen in which a drug formulation is housed. The device also includes a buoyancy retention portion, which includes a volume of entrapped air or a gas-generating or effervescent powder which will generate a volume of entrapped air following contact with urine in the bladder. The buoyancy retention portion may include a water permeable and/or biodegradable wall, which can release the entrapped air following drug release, to cause the device to sink into the bladder neck to facilitate device expulsion without the need for a device retrieval medical procedure.


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