The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2016

Filed:

Jun. 28, 2012
Applicants:

Rodney Martin Donlan, Atlanta, GA (US);

Susan Marie Lehman, Atlanta, GA (US);

Andres J. Garcia, Atlanta, GA (US);

Inventors:

Rodney Martin Donlan, Atlanta, GA (US);

Susan Marie Lehman, Atlanta, GA (US);

Andres J. Garcia, Atlanta, GA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 29/10 (2006.01); A01N 63/00 (2006.01); A61L 27/34 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61L 29/08 (2006.01); A61L 29/14 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); A61L 15/60 (2006.01); A61L 15/36 (2006.01); A61L 27/36 (2006.01); A61L 29/16 (2006.01); A61L 15/44 (2006.01); A61K 35/76 (2015.01); A61M 25/00 (2006.01);
U.S. Cl.
CPC ...
A61L 29/106 (2013.01); A01N 63/00 (2013.01); A61L 15/36 (2013.01); A61L 15/44 (2013.01); A61L 15/60 (2013.01); A61L 27/34 (2013.01); A61L 27/3637 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 29/08 (2013.01); A61L 29/085 (2013.01); A61L 29/145 (2013.01); A61L 29/16 (2013.01); A61L 31/10 (2013.01); A61L 31/145 (2013.01); A61L 31/16 (2013.01); A61K 35/76 (2013.01); A61L 2300/102 (2013.01); A61L 2300/104 (2013.01); A61L 2300/404 (2013.01); A61L 2300/406 (2013.01); A61L 2300/606 (2013.01); A61M 2025/0056 (2013.01); C12N 2795/10132 (2013.01); C12N 2795/10232 (2013.01); C12N 2795/10332 (2013.01);
Abstract

Medical devices that are resistant to biofilm development and methods of the manufacture of biofilm resistant medical devices are provided. One or more bacteriophages are tethered to the surface of a medical device or a hydrogei-type coating on the surface of the device by covalent bonding while maintaining bacteriophage infective or lytic activity. The presence of the bacteriophages on a medical device, such as an indwelling medical device, prevents biofilm formation or reduces existing biofilm formation on the surface of the device when in use. These devices address the long felt need for biofilm resistant devices that increase safety and reduce complications normally associated with prior indwelling or other medical devices.


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