The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2016

Filed:

Feb. 22, 2011
Applicants:

Kiyoshi Kanazawa, Aichi, JP;

Kazuhiko Nonomura, Shizuoka, JP;

Takako Okumura, Aichi, JP;

Shinichi Koizumi, Aichi, JP;

Inventors:

Kiyoshi Kanazawa, Aichi, JP;

Kazuhiko Nonomura, Shizuoka, JP;

Takako Okumura, Aichi, JP;

Shinichi Koizumi, Aichi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/44 (2006.01); A01N 37/12 (2006.01); A01N 47/28 (2006.01); A61K 31/17 (2006.01); C07D 513/02 (2006.01); C07D 515/02 (2006.01); C07D 211/72 (2006.01); A61K 45/06 (2006.01); A61K 31/38 (2006.01); A61K 31/437 (2006.01); A61K 31/4412 (2006.01); A61K 31/443 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/38 (2013.01); A61K 31/437 (2013.01); A61K 31/44 (2013.01); A61K 31/443 (2013.01); A61K 31/4412 (2013.01);
Abstract

This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a pharmaceutical composition for the treatment of immune disease or allergy which comprises a therapeutically effective amount of a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof. Further this invention relates to a method for the treatment of immune disease or allergy in an animal subject including a mammalian subject, which comprises administering to the animal subject including a mammalian subject a compound of the formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof.


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