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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9457073 B1

PDFFull Text
Expired
Date of Patent:
Oct. 04, 2016

Filed:

Sep. 24, 2013

Live attenuated replication-competent arteriviruses having decreased dub/deisgylating activity

Applicants:

Leiden University Medical Center, Leiden, NL;

University of Manitoba, Winnipeg, CA;

Inventors:

Marjolein Kikkert, Sassenheim, NL;

Brian Leonard Mark, Winnipeg, CA;

Puck Bertyne van Kasteren, Bussum, NL;

Terrence William James, Grande Pointe, CA;

Eric John Snijder, Bodegraven, NL;

Assignee:

University of Manitoba, Winnipeg, CA;

Attorney:
Primary Examiner:

Shanon A Foley

Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/42 (2006.01); A61K 9/02 (2006.01); C12N 7/00 (2006.01); A61K 39/02 (2006.01); A61K 39/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 39/02 (2013.01); A61K 39/40 (2013.01); A61K 39/42 (2013.01); C12N 7/00 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/552 (2013.01); C07K 2299/00 (2013.01); C12N 2770/10021 (2013.01); C12N 2770/10034 (2013.01); C12N 2770/10062 (2013.01);
Abstract

The present invention relates to replication-competent Arteriviruses having a decreased DUB/deISGylating activity due to a mutation in the PLP2 domain of the non-structural protein nsp2, to their use as a medicament, their use as a vaccine and in prophylaxis, to vaccines comprising such Arteriviruses and to Arteriviral PLP2-ubiquitin complexes.

Find Patent Forward Citations

Kikkert, Marjolein. (2016). Live attenuated replication-competent arteriviruses having decreased dub/deisgylating activity (U.S. Patent No. 9457073). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9457073

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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