The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
May. 14, 2015
Sanofi-aventis Deutschland Gmbh, Frankfurt, DE;
Harald Rau, Heidelberg, DE;
Felix Cleemann, Heidelberg, DE;
Ulrich Hersel, Heidelberg, DE;
Silvia Kaden-Vagt, Heidelberg, DE;
Torben Lessmann, Mannheim, DE;
Thomas Wegge, Heidelberg, DE;
SANOFI-AVENTIS DEUTSCHLAND GMBH, Frankfurt, DE;
Abstract
The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising an insulin linker conjugate D-L, wherein D represents the insulin moiety; and -L is a non-biologically active linker moiety -Lrepresented by formula (I), wherein the dashed line indicates the attachment to one of the amino groups of the insulin by forming an amide bond. The invention further relates to pharmaceutical compositions comprising said prodrugs as well as their use as a medicament for treating or preventing diseases or disorders which can be treated by insulin.