The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2016

Filed:

Sep. 26, 2013
Applicants:

Whitehead Institute, Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Boston University, Boston, MA (US);

The General Hospital Corporation, Boston, MA (US);

Inventors:

Ifat Rubin-Bejerano, Belmont, MA (US);

Gerald R. Fink, Chestnut Hill, MA (US);

Claudia Abeijon, Worcester, MA (US);

Daniel S. Kohane, Newton, MA (US);

Jason E Fuller, Boston, MA (US);

Robert S. Langer, Newton, MA (US);

Assignees:

Whitehead Institute, Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Trustees of Boston University, Boston, MA (US);

The General Hospital Corporation, Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/716 (2006.01); A61K 45/06 (2006.01); A61K 36/09 (2006.01); C08B 37/00 (2006.01); A61K 36/064 (2006.01); A61K 47/48 (2006.01); C08J 3/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/716 (2013.01); A61K 36/064 (2013.01); A61K 36/09 (2013.01); A61K 45/06 (2013.01); A61K 47/4823 (2013.01); A61K 47/48538 (2013.01); C08B 37/0024 (2013.01); C08J 3/126 (2013.01); C08J 3/128 (2013.01); C08J 2300/16 (2013.01); C08J 2325/06 (2013.01); C08J 2367/04 (2013.01); C08J 2400/16 (2013.01); C08J 2405/00 (2013.01);
Abstract

This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.


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