The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2016
Filed:
Oct. 11, 2013
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Vinay Girijavallabhan, Whippany, NJ (US);
Stephane Bogen, Somerset, NJ (US);
Weidong Pan, Hillsborough, NJ (US);
Qun Dang, Westfield, NJ (US);
Ian Davies, Princeton, NJ (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/12 (2006.01); C07H 19/23 (2006.01); C07D 487/04 (2006.01); A61K 31/706 (2006.01); A61K 31/53 (2006.01); A61P 31/14 (2006.01); A61K 45/06 (2006.01); A61K 31/7056 (2006.01); A61K 38/21 (2006.01); C07H 7/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/706 (2013.01); A61K 31/7056 (2013.01); A61K 38/21 (2013.01); A61K 45/06 (2013.01); C07D 487/04 (2013.01); C07H 7/06 (2013.01);
Abstract
2'-disubstituted substituted nucleoside derivatives of formula (I) and pharmaceutically acceptable salts thereof are disclosed: (1), wherein A is Nor NHand X, Y, R, R, R, R, Rand Rare as defined herein. Compositions comprising at least one 2′-disubstituted nucleoside derivative, and methods of using the 2′-disubstituted nucleoside derivatives for treating or preventing HCV infection in a patient are disclosed.