The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2016

Filed:

Feb. 15, 2012
Applicants:

François Malouin, Eastman, CA;

Gabriel Mitchell, Shawinigan-Sud, CA;

Kamal Bouarab, Sherbrooke, CA;

Eric Marsault, Sherbrooke, CA;

Felix Chagnon, Waterloo, CA;

Simon Boulanger, Sherbrooke, CA;

Isabelle Guay, Magog, CA;

Inventors:

François Malouin, Eastman, CA;

Gabriel Mitchell, Shawinigan-Sud, CA;

Kamal Bouarab, Sherbrooke, CA;

Eric Marsault, Sherbrooke, CA;

Felix Chagnon, Waterloo, CA;

Simon Boulanger, Sherbrooke, CA;

Isabelle Guay, Magog, CA;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A01N 45/00 (2006.01); A61K 31/7036 (2006.01); C07J 43/00 (2006.01); A61K 31/395 (2006.01); A61L 2/16 (2006.01); C07J 7/00 (2006.01); C07J 41/00 (2006.01); C07J 51/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A01N 45/00 (2013.01); A61K 31/395 (2013.01); A61K 31/7036 (2013.01); C07J 43/003 (2013.01); C07J 43/006 (2013.01); A61L 2/16 (2013.01); C07J 7/002 (2013.01); C07J 7/006 (2013.01); C07J 7/007 (2013.01); C07J 7/0085 (2013.01); C07J 41/005 (2013.01); C07J 41/0055 (2013.01); C07J 51/00 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention includes novel compounds based on the tomatidine skeleton as well as composition comprising these compounds alone and in combination with known compounds, which exhibit antimicrobial activity against extracellular or intracellular electron transport-deficient microbes and/or increase the antimicrobial activity of aminoglycoside antibiotics against their targets, and which are useful as antibacterial agents for treatment or prophylaxis of monomicrobiotic or polymicrobic bacterial infections or for the reduction of antibiotic resistance development in animals or in humans, or for use as antiseptics or agents for sterilization or disinfection.


Find Patent Forward Citations

Loading…