The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9457030 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 04, 2016

Filed:

Oct. 29, 2013
Applicant:

Board of Regents of the University of Nebraska, Lincoln, NE (US);

Inventor:

Tammy Kielian, Omaha, NE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/522 (2006.01); A61K 31/4545 (2006.01); A61K 31/4015 (2006.01); A61K 31/44 (2006.01); A61K 31/4425 (2006.01); A61K 45/06 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 31/522 (2013.01); A61K 31/4015 (2013.01); A61K 31/44 (2013.01); A61K 31/4425 (2013.01); A61K 31/4545 (2013.01); A61K 38/177 (2013.01); A61K 45/06 (2013.01);
Abstract

Provided are materials and methods for the prevention and treatment of Juvenile Neuronal Ceroid Lipofuscinosis comprising administration of an effective amount of at least one of a hemi-channel inhibitor or a phosphodiesterase-4 inhibitor. In some embodiments, the methods comprise administration of an effective amount of each of a hemi-channel inhibitor and a phosphodiesterase-4 inhibitor. Also provided are pharmaceutical compositions comprising a hemi-channel inhibitor or a phosphodiesterase-4 inhibitor, as well as kits comprising at least one effective dose of a hemi-channel inhibitor or a phosphodiesterase-4 inhibitor or a combination of both.


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