The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Jul. 19, 2011
Juan Ruiz, Acton, MA (US);
Marcia Sellos-moura, West Newbury, MA (US);
Michael F. Concino, Bolton, MA (US);
Pan Luying, Newton, MA (US);
Paolo Martini, Boston, MA (US);
Bettina Strack-logue, Somerville, MA (US);
Scott Alderucci, Sutton, MA (US);
Juan Ruiz, Acton, MA (US);
Marcia Sellos-Moura, West Newbury, MA (US);
Michael F. Concino, Bolton, MA (US);
Pan Luying, Newton, MA (US);
Paolo Martini, Boston, MA (US);
Bettina Strack-Logue, Somerville, MA (US);
Scott Alderucci, Sutton, MA (US);
SHIRE HUMAN GENETIC THERAPIES, INC., Lexington, MA (US);
Abstract
Described herein are isolated nucleic acid molecules comprising nucleotide sequence encoding mannose receptor, C type 1 (MRC1) wherein the 5' region of the nucleotide sequence encoding MRC1 is codon optimized; cells comprising such nucleic acid molecules; and methods of detecting antibody production, e.g., neutralizing antibody production, in a subject being treated for Gaucher disease using such cells.