The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2016
Filed:
Sep. 20, 2012
Applicant:
The George Washington University, Washington, DC (US);
Inventors:
Norman H. Lee, Dayton, MD (US);
Steven R. Patierno, Chapel Hill, NC (US);
Bi-Dar Wang, Potomac, MD (US);
Assignee:
The George Washington University, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12Q 1/68 (2006.01); C07K 14/47 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C07K 14/47 (2013.01); C07K 14/4748 (2013.01); C12N 15/1137 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01);
Abstract
Disclosed are novel splicing variants of the genes associated with prostate cancer risk and survival, particularly splicing variants of PIK3CD, FGFR3, TSC2, RASGRP2, ITGA4, MET, NF1 and BAK1. The disclosure also relates risk assessment, detection, diagnosis, or prognosis of prostate cancer. More specifically, this disclosure relates to the detection of certain splicing variants of PIK3CD, FGFR3, TSC2, RASGRP2, ITGA4, MET, NF1 and BAK1.